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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
24.55
Human Site:
S479
Identified Species:
36
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S479
S
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S479
S
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y912
D
K
G
R
F
E
L
Y
R
A
T
F
Y
A
A
Dog
Lupus familis
XP_849292
706
81555
S479
S
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S479
S
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S479
S
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
V481
S
C
H
K
F
E
L
V
R
A
T
F
Y
A
A
Chicken
Gallus gallus
NP_001006133
699
80179
Y456
D
K
G
R
F
D
L
Y
R
A
T
F
Y
G
A
Frog
Xenopus laevis
Q7LZQ8
671
76506
P438
Q
V
G
R
F
K
E
P
H
A
V
F
Y
A
A
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
P438
Q
V
G
K
F
K
E
P
H
A
V
F
Y
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
H419
T
L
A
L
Q
F
L
H
T
H
G
V
I
Y
R
Honey Bee
Apis mellifera
XP_394743
624
71014
L414
A
A
E
I
W
S
G
L
N
F
L
H
K
K
G
Nematode Worm
Caenorhab. elegans
P34722
704
80280
A474
Q
I
K
K
F
D
E
A
R
T
R
F
Y
A
C
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
K416
Q
N
I
T
G
E
T
K
A
S
T
F
C
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
R925
N
Q
R
L
S
V
R
R
A
K
F
Y
A
A
E
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R918
R
G
M
F
G
T
K
R
A
Q
F
Y
A
A
E
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
86.6
60
40
46.6
N.A.
6.6
0
46.6
13.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
93.3
66.6
46.6
46.6
N.A.
13.3
13.3
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
0
7
19
63
0
0
13
75
63
% A
% Cys:
0
38
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
13
0
0
0
0
44
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
19
19
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
7
69
7
0
0
0
7
13
75
0
0
0
% F
% Gly:
0
7
25
0
13
0
7
0
0
0
7
0
0
13
7
% G
% His:
0
0
38
0
0
0
0
7
13
7
0
7
0
0
0
% H
% Ile:
0
7
7
7
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
13
7
50
0
13
7
7
0
7
0
0
7
7
0
% K
% Leu:
0
7
0
13
0
0
57
7
0
0
7
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
25
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
7
0
7
19
0
0
7
13
57
0
7
0
0
0
7
% R
% Ser:
38
0
0
0
7
7
0
32
0
7
0
0
0
0
0
% S
% Thr:
7
0
0
7
0
7
7
0
7
7
57
0
0
0
7
% T
% Val:
0
13
0
0
0
7
0
7
0
0
13
7
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
13
69
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _